Analysis of Immune Activation in the Peripheral Blood of Patients with ALS
Study Purpose:
The purpose of this study is to learn more about the role of the immune system in ALS and find unique biological markers, which could be used to develop new therapies.
Disease:
Amyotrophic Lateral Sclerosis (ALS), Familial ALS, Sporadic ALS, Healthy Volunteer, Healthy Volunteer with a Family History of ALSStudy Type:
Observational StudyStudy Category:
Biomarkers/ImagingStudy Status:
Not enrollingPhase:
Not ApplicableStudy Chair(s)/Principal Investigator(s):
James D. Berry, MD, MPH (Massachusetts General Hospital)
Clinicaltrials.gov ID (11 digit #):
Neals Affiliated?
YesCoordinating Center Contact Information
Massachusetts General HospitalMaryAngel Jeon / .(JavaScript must be enabled to view this email address) / 617-724-9196
.(JavaScript must be enabled to view this email address) Neurological Clinical Research Institute (NCRI)
165 Cambridge Street, Suite 600
Boston, Massachusetts 02114 United States
Full Study Summary:
The purpose of the research study is to collect blood samples from people with amyotrophic lateral sclerosis (ALS) and control volunteers. Through comparison of these samples, the researchers hope to learn more about the role of the immune system in ALS, as well as find unique biological markers, which could be used to develop new therapies.
Study Sponsor:
Departmental fundsParticipant Duration:
Control subjects will participate in a one-time blood draw and ALS subjects will participate in up to 7 brief sample collection visits every 3 months. Each visit will require up to 1 hour of the subject™s time. All visits will take place at the main campus of Massachusetts General Hospital.