Cervical Spinal Cord Metabolism and Microstructure in Amyotrophic Lateral Sclerosis(ALS)
The investigators are wanting to know if magnetic resonance imaging can accurately provide an early diagnosis of amyotrophic lateral sclerosis (ALS).
Disease:Amyotrophic Lateral Sclerosis (ALS), Familial ALS, Sporadic ALS, Healthy Volunteer
Study Type:Interventional Trial
Study Chair(s)/Principal Investigator(s):
Bradley Foerster, M.D. University of Michigan Hospital
Clinicaltrials.gov ID (11 digit #):NCT02000713
Coordinating Center Contact InformationUniversity of Michigan
Full Study Summary:
Currently there is no definitive diagnostic test for amyotrophic lateral sclerosis (ALS). The investigators goal is to determine if magnetic resonance imaging can provide an accurate diagnosis of ALS by looking at chemical concentrations in the spinal cord at the neck level which show up in MRI imaging and compare these chemical concentrations to corresponding measures in healthy control subjects.
Study Sponsor:University of Michigan
Estimated Study Start Date:10/01/2013
Estimated Study Completion Date:12/31/2018
Posting Last Modified Date:01/11/2018
Date Study Added to alsconsortium.org:08/18/2015
Time since Symptom Onset:
Time since Diagnosis:
Can participants use Riluzole?
1. Adults age 18 to 80 years of age.
-Do not have active substance abuse
-Do not have co-morbid psychiatric disease
-Do not have opportunistic central nervous system infection
-Do not have cerebrovascular disease
-Do not have a contraindication for magnetic resonance imaging(MRI)(e.g. cardiac pacemaker, ferromagnetic or metallic implants).
-Are not pregnant
-Have not had cervical spinal surgery(neck) -
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