Clinical Research in ALS
Study Purpose:
CRiALS is an umbrella protocol through which people are recruited to participate in a range of research studies being conducted by the ALS Research Collaboration (ARC).
Disease:
Amyotrophic Lateral Sclerosis (ALS), Familial ALS, Sporadic ALS, Healthy Volunteer, Healthy Volunteer with a Family History of ALSStudy Type:
Observational StudyStudy Category:
Diseases , Study Type , Study Status , Phase , GenderStudy Status:
EnrollingPhase:
Not ApplicableStudy Chair(s)/Principal Investigator(s):
Michael Benatar, MD, PhD. University of Miami
Clinicaltrials.gov ID (11 digit #):
NCT00136500Neals Affiliated?
NoCoordinating Center Contact Information
University of MiamiAnne-Laure Grignon, MD / .(JavaScript must be enabled to view this email address) / 888-413-9315
Danielle Dauphin / .(JavaScript must be enabled to view this email address) / 888-413-9315
Miami, Florida 33136 United States
Full Study Summary:
Research goals include elucidation of the complex relationship between ALS and related neurodegenerative disorders, development of both wet and dry biomarkers of disease, and delineation of the full course of the natural history of disease from the early pre-symptomatic stages through established and even late-stage disease. These goals are accomplished through the recruitment and evaluation of patients with ALS and related diseases, family members (including people at genetic risk for ALS, but who are not yet affected), and healthy controls.