Microbiome Assessment in People with ALS (MAP ALS)
Study Purpose:The purpose of the research study is to collect stool samples from people with amyotrophic lateral sclerosis (ALS) and healthy volunteers. Through comparison of these samples, the researchers hope to learn more about the microbiome (i.e. bacterial strains) in the stool of patients with ALS, as well as find unique biological markers, which could be used to develop new therapies.
Disease:Amyotrophic Lateral Sclerosis (ALS), Familial ALS, Sporadic ALS, Healthy Volunteer, Healthy Volunteer with a Family History of ALS
Study Type:Observational Study
Study Status:Active, currently recruiting
Study Chair(s)/Principal Investigator(s):Katharine Nicholson, MD, Massachusetts General Hospital
Clinicaltrials.gov ID (11 digit #):
Coordinating Center Contact InformationMassachusetts General Hospital
Boston, Massachusetts 02114 United States
Full Study Summary:We will collect stool samples from people with ALS and compare these to samples collected from people without ALS. Samples will be sent to the Broad Institute for analysis.
Study Sponsor:ALS Finding a Cure
Participant Duration:All eligible subjects will provide clinical information and participate in a one-time stool collection. ALS subjects will have the option to participate in up to 2 additional brief visits collecting only clinical information, 3 months and 6 months after the first visit.
Estimated Enrollment:100 with ALS & 100 Controls
Estimated Study Start Date:12/31/2015
Estimated Study Completion Date:11/02/2016
Posting Last Modified Date:07/31/2016
Date Study Added to alsconsortium.org:01/19/2016
Time since Symptom Onset:
Time since Diagnosis:
Can participants use Riluzole?Yes
You must be at least 18 years of age, answer brief questions about your medical and family history, and give a stool samples.
- Site Contact Information