Microbiome Assessment in People with ALS (MAP ALS)
Study Purpose:
The purpose of the research study is to collect stool samples from people with amyotrophic lateral sclerosis (ALS) and healthy volunteers. Through comparison of these samples, the researchers hope to learn more about the microbiome (i.e. bacterial strains) in the stool of patients with ALS, as well as find unique biological markers, which could be used to develop new therapies.
Disease:
Amyotrophic Lateral Sclerosis (ALS), Familial ALS, Sporadic ALS, Healthy Volunteer, Healthy Volunteer with a Family History of ALSStudy Type:
Observational StudyStudy Category:
Biomarkers/ImagingStudy Status:
Not enrollingPhase:
Not ApplicableStudy Chair(s)/Principal Investigator(s):
Katharine Nicholson, MD, Massachusetts General Hospital
Clinicaltrials.gov ID (11 digit #):
Neals Affiliated?
YesCoordinating Center Contact Information
Massachusetts General HospitalMaryangel Jeon / .(JavaScript must be enabled to view this email address) / 617-724-9196
.(JavaScript must be enabled to view this email address) 165 Cambridge Street
Boston, Massachusetts 02114 United States
Full Study Summary:
We will collect stool samples from people with ALS and compare these to samples collected from people without ALS. Samples will be sent to the Broad Institute for analysis.
Study Sponsor:
ALS Finding a CureParticipant Duration:
All eligible subjects will provide clinical information and participate in a one-time stool collection. ALS subjects will have the option to participate in up to 2 additional brief visits collecting only clinical information, 3 months and 6 months after the first visit.