Determination of Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)
Individuals with th Amyotrophic Lateral Sclerosis are at high risk for swallowing impairment (dysphagia) which leads to malnutrition, decreased pulmonary health, aspiration and aspiration pneumonia. These sequelae necessitate timely identification of at risk individuals to ensure optimal management of oral intake and pulmonary function. The purpose of this study is to evaluate the discriminant ability of several non-invasive screening tools at detecting swallowing impairment in individuals with ALS.
Disease:Amyotrophic Lateral Sclerosis (ALS)
Study Type:Interventional Trial
Study Category:Device, Other
Study Status:Active, currently recruiting
Study Chair(s)/Principal Investigator(s):
Emily Plowman, Ph.D., University of Florida
Clinicaltrials.gov ID (11 digit #):NCT02710162
Coordinating Center Contact InformationUniversity of Florida
Full Study Summary:
This research study is being performed to determine how accurate different screening tools or tests are at identifying swallowing problems associated with Amyotrophic Lateral Sclerosis (ALS).
As a participant one evaluation will be performed at the University of Florida Swallowing Systems Core laboratory located at Shands Hospital, Gainesville will take place. This will take approximately two-hours. During this evaluation an videofluoroscopy (X-ray of swallowing), cough tests, tongue function test and questionnaires will be completed.
Study Sponsor:University of Florida
Estimated Study Start Date:02/29/2016
Estimated Study Completion Date:02/28/2017
Posting Last Modified Date:11/30/2016
Date Study Added to alsconsortium.org:05/01/2016
Time since Symptom Onset:
Time since Diagnosis:
Can participants use Riluzole?
-diagnosis of probable or definite ALS
-allergies to barium or capsaicin
-tracheotomy or mechanical ventilation
-absence of diaphragmatic pacer
-respiratory disease (COPD).
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