Longitudinal Study of Innate Lymphoid Cells in Peripheral Blood in ALS
Study Purpose:
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by progressive muscle weakness and eventual death. Studies demonstrate that the immune system plays a key role in ALS progression; however, the role of the immune system is unclear, as various aspects can play both a beneficial and detrimental role in the disease course. Attempts to universally suppress the immune system in ALS patients have at best had negligible effects on progression or at worst accelerated the disease. Thus, there is a critical need to identify immune cell populations to serve as biomarkers and therapeutic targets.
Disease:
Amyotrophic Lateral Sclerosis (ALS), Familial ALS, Sporadic ALS, Healthy VolunteerStudy Type:
Observational StudyStudy Category:
Blood drawStudy Status:
EnrollingPhase:
Not ApplicableStudy Chair(s)/Principal Investigator(s):
Ben Murdock, PhD, University of Michigan
Clinicaltrials.gov ID (11 digit #):
NCT03090932Neals Affiliated?
NoCoordinating Center Contact Information
University of MichiganBlake Swihart / .(JavaScript must be enabled to view this email address) / 734-763-8284
.(JavaScript must be enabled to view this email address) Ann Arbor, Michigan 48109 United States