ALS Sample Repository
The purpose of this study is to acquire biofluid samples from a diverse cohort of participants to create a living library for researchers across the world to learn more about the biomarkers of the ALS disease state.
Disease:Amyotrophic Lateral Sclerosis (ALS), Primary Lateral Sclerosis (PLS), Hereditary Spastic Paraplegia (HSP), Healthy Volunteer, Healthy Volunteer with a Family History of ALS
Study Type:Observational Study
Study Chair(s)/Principal Investigator(s):
James D. Berry, MD, MPH (Massachusetts General Hospital)
Clinicaltrials.gov ID (11 digit #):
Coordinating Center Contact InformationMassachusetts General Hospital
Boston, Massachusetts 02214 United States
Full Study Summary:
We are developing a diverse living library of biofluid samples (blood, spinal fluid, urine) from people of different ages, ethnicities, and sexes, from healthy volunteers, people with amyotrophic lateral sclerosis (ALS), and motor neuron disease (MND), as well as other neurological diseases that may mimic motor neuron diseases. The samples collected will be stored and used for ALS research conducted globally to answer questions related to cause, prevention, treatment, and hereditability of ALS. Participants must be at least 20 years of age and be able to answer brief questions about their medical and family history, as well as be willing to have blood and/or CSF drawn for the study.
Study Sponsor:Project ALS, Winthrop Family Scholar in ALS Research and Clinical Care
Participants will visit 165 Cambridge St. in Boston, MA 1 to 5 times over the course of two years. Only one visit is required, and additional visits are completely optional. Each visit lasts about 2 hours.
Estimated Study Start Date:07/14/2006
Estimated Study Completion Date:
Posting Last Modified Date:10/08/2021
Date Study Added to alsconsortium.org:10/08/2021
Parking will be compensated for participants. $10 will be compensated for a blood draw and $100 for a lumbar puncture.
Time since Symptom Onset:N/A
Time since Diagnosis:N/A
Can participants use Riluzole?Yes
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