Social Cognition in Patients With Amyotrophic Lateral Sclerosis

Study Purpose:

Amyotrophic Lateral Sclerosis, also known as Charcot disease, is a neurodegenerative disease evidenced by gradual paralysis of the muscles involved in voluntary motor function. The clinical hallmark of Amyotrophic Lateral Sclerosis is the combination of upper and lower motor neuron signs and symptoms. The most recent studies suggest that up to 50% of Amyotrophic Lateral Sclerosis patients demonstrate mild to moderate cognitive disturbance. Impaired social cognition, including a deficit in the recognition of facial emotions and the identification of vocal prosody, is recognized as a part of the cognitive phenotype of Amyotrophic Lateral Sclerosis, with crucial implications for patients' and caregivers' training. However, studies remain scarce and the data acquired must be supported. The evolution of these manifestations during the disease is still poorly understood.

In this study the investigators aim to assess the social cognition capacities of patients with Amyotrophic Lateral Sclerosis compared to healthy matched control subjects.

Study Status:

Recruiting

Disease:

Social Cognition

Study Type:

Interventional

Type of Intervention:

N/A

Intervention Name:

neuropsychological test

Placebo:

Phase:

N/A

Study Chair(s)/Principal Investigator(s):

N/A

Clinicaltrials.gov ID:

NCT04406675

Neals Affiliated?

No

Coordinating Center Contact Information

Study Sponsor:

University Hospital, Angers

Estimated Enrollment:

74

Estimated Study Start Date:

09 / 21 / 2020

Estimated Study Completion Date:

09 / 01 / 2023

Posting Last Modified Date:

01 / 05 / 2021

Date Study Added to neals.org:

05 / 28 / 2020