Jeffrey D. Rothstein MD, PhD. is the John Griffin Director of the Brain Science Institute and Professor of Neurology and Neuroscience at Johns Hopkins University, Baltimore, MD, USA. He is the Founder and Director of the Robert Packard Center for ALS Research at Johns Hopkins, the largest collaborative academic organization dedicated towards understanding ALS and developing novel therapeutics and the Director of the Muscular Dystrophy Association ALS Clinic. He received a B.A. in Neuroscience from Colgate University, Johns Hopkins University, Baltimore, Maryland, USA, a Masters at the University of Chicago, Chicago IL, USA and his MD and Ph.D. in Physiology and Biophysics from the University of Illinois, Chicago, IL, USA. He did Neurology residency and neuromuscular fellowship training at Johns Hopkins University, Baltimore, MD USA. He has been the principal and/or local investigator in almost a dozen National or International trials in ALS His laboratory research interests range from basic neurobiology of CNS glia and their role in regulating neurotransmission, to the pathophysiology of neurodegenerative disease, focusing on ALS. Specifically, he uses model systems including rodent and human IPS models and human tissue to dissect the underlying mechanisms of neuronal and glial injury in ALS as a means of illuminating effective therapies. He is the author of over 250 peer-reviewed articles on basic and clinical neuroscience. He holds more than a dozen patents on candidate drugs and biomarkers for ALS and Neurodegenerative disease.