Sabrina Paganoni, MD, PhD, is the Co-Director of the Neurological Research Institute at the Massachusetts General Hospital, Assistant Professor at Harvard Medical School and physician investigator at the Healey & AMG Center for ALS at Mass General. Dr Paganoni’s research focuses on clinical trials and therapy development for ALS. She has served as Principal Investigator of several ALS clinical trials including the CENTAUR trial (a trial of AMX0035 in ALS). She is also the co-Principal Investigator of the HEALEY ALS Platform Trial, the first platform trial for ALS in the world. Her research has been funded by the NIH, non-profits, and industry; she published more than 100 peer-reviewed manuscripts and received several awards for her work including the 2021 Top 10 Clinical Research Achievement Award for the CENTAUR trial. She is also passionate about clinical care innovation and access to research for people with ALS. She co-chairs the Upper Motor Neuron Task Force, the Technology Committee and the Recruitment/Retention/Experience Committee at NEALS.